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Background: Hypertension is a serious health problem that is increasing every year. Lifestyle changes such as lack of movement become one of the factors developing this disease. This study was conducted to see the effectiveness gripping exercise of handgrip tool on changes in blood pressure in hypertension patients. Methods: The study used a method of quasi experiment pre and post test with one intervention group. This interventions was given to 16 adult respondents for 5 consecutive days. Assessment of the effectiveness of this therapy is done by measuring the respondent's blood pressure before and after the intervention. Results: The results showed that there was effectiveness gripping exercise of handgrip tool in on systolic blood pressure and diastolic blood pressure (p-value <0.05). So, gripping exercise of handgrip tool intervention can lower blood pressure in people with hypertension. Conclutions: The effectiveness of this therapy must also be done in conjunction with maintaining a lifestyle and regularly taking antihypertensive medication.